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Jackson B. Gibbs

United States Military Academy

42

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Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects (binding site/G protein/mutagenesis/mammalian transformation/yeast lethality)

2016
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Potent 2-[(pyrimidin-4-yl)amine}-1,3-thiazole-5-carbonitrile-based inhibitors of VEGFR-2 (KDR) kinase.

2006 Bioorganic & Medicinal Chemistry Letters
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The synthesis and biological evaluation of a series of potent dual inhibitors of farnesyl and geranyl-Geranyl protein transferases.

2002 Bioorganic & Medicinal Chemistry Letters
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Oxo-piperazine Derivatives of N-Arylpiperazinones as Inhibitors of Farnesyltransferase

2001 Bioorganic & Medicinal Chemistry Letters
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Antitumor Efficacy of a Farnesyltransferase Inhibitor in Transgenic Mice

2001
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4 Farnesyltransferase inhibitors

2001 The Enzymes
- Jackson B. Gibbs
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Mechanism-Based Target Identification and Drug Discovery in Cancer Research

2000 Science
- Jackson B. Gibbs
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Imidazole-Containing Diarylether and Diarylsulfone Inhibitors of Farnesyl-Protein Transferase.

2000 ChemInform
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Imidazole-containing diarylether and diarylsulfone inhibitors of farnesyl-protein transferase

1999 Bioorganic & Medicinal Chemistry Letters
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Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase.

1999 Bioorganic & Medicinal Chemistry Letters
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