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Joelle M. Onorato

Bristol-Myers Squibb

25

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193

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Identification of 6-Hydroxypyrimidin-4(1H)-one-3-carboxamides as Potent and Orally Active APJ Receptor Agonists.

2021 ACS Medicinal Chemistry Letters
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Identification of a Hydroxypyrimidinone Compound (21) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure.

2021 Journal of Medicinal Chemistry
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Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate.

2021 Journal of Medicinal Chemistry
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Identification of 6-hydroxy-5-phenyl sulfonylpyrimidin-4(1H)-one APJ receptor agonists.

2021 Bioorganic & Medicinal Chemistry Letters
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In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure.

2021 Circulation-heart Failure
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Qualified method for the estimation of di-18:1 bis(monoacylglycero)phosphate in urine, a noninvasive biomarker to monitor drug-induced phospholipidosis.

2020 Bioanalysis
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Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) which Demonstrate HDL-C Increase In Vivo

2020 Journal of Medicinal Chemistry
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Discovery and SAR of Aryl Hydroxy Pyrimidinones as Potent Small Molecule Agonists of the GPCR APJ

2020 Bioorganic & Medicinal Chemistry Letters
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Discovery and Structure Activity Relationships of 7-Benzyl Triazolopyridines as Stable, Selective, and Reversible Inhibitors of Myeloperoxidase

2020 Bioorganic & Medicinal Chemistry
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Corrigendum to “Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase” [Bioorg. Med. Chem. Lett. 29 (2019) 1918–1921]

2019 Bioorganic & Medicinal Chemistry Letters
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