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Robert Paul Brigance
Robert Paul Brigance
Bristol-Myers Squibb
Chemistry
Biochemistry
In vitro
Stereochemistry
Organic chemistry
5
Papers
69
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Identification of a Hydroxypyrimidinone Compound (21) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure.
2021
Journal of Medicinal Chemistry
Wei Meng
Zulan Pi
Robert Paul Brigance
Karen A. Rossi
William A. Schumacher
Jeffrey S. Bostwick
Peter S. Gargalovic
Joelle M. Onorato
Chiuwa E. Luk
Claudia Generaux
Tao Wang
Ruth R. Wexler
Heather Finlay
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Estimation of the extent of in vivo formation of a mutagenic aromatic amine from a potent thyromimetic compound: correlation of in vitro and in vivo findings.
2011
Chemical Research in Toxicology
Kamelia Behnia
Georgia Cornelius
Jian Wang
Petia Shipkova
Susan Johnghar
William N. Washburn
Robert Paul Brigance
Paul Stetsko
Andrew Henwood
James P. Wojciechowski
Punit Marathe
A. David Rodrigues
W. Griffith Humphreys
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Citations (2)
Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes.
2010
Bioorganic & Medicinal Chemistry Letters
Robert Paul Brigance
Wei Meng
Aberra Fura
Thomas Harrity
Aiying Wang
Robert Zahler
Mark S. Kirby
Lawrence G. Hamann
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Citations (44)
Synthesis, SAR, and atropisomerism of imidazolopyrimidine DPP4 inhibitors.
2010
Bioorganic & Medicinal Chemistry Letters
Stephen P. O'connor
Ying Wang
Ligaya M. Simpkins
Robert Paul Brigance
Wei Meng
Aiying Wang
Mark S. Kirby
Carolyn A. Weigelt
Lawrence G. Hamann
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Citations (13)
Thyroid receptor ligands. Part 8: Thyromimetics derived from N-acylated-α-amino acid derivatives displaying modulated pharmacological selectivity compared with KB-141
2007
Bioorganic & Medicinal Chemistry Letters
Neeraj Garg
Yi-Lin Li
Ana Maria Garcia Collazo
Chris Litten
Denis E. Ryono
Minsheng Zhang
Yolanda Caringal
Robert Paul Brigance
Wei Meng
William N. Washburn
Peter Agback
Karin Mellström
Stefan Rehnmark
Mahmoud Rahimi-Ghadim
Thomas Anders Norin
Marlena Grynfarb
Johnny Sandberg
Gary J. Grover
Johan Malm
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Citations (10)
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