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Stanley Wertheimer

Hoffmann-La Roche

16

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279

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Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors.

2011 Bioorganic & Medicinal Chemistry Letters
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Discovery of Orally Active Carboxylic Acid Derivatives of 2-Phenyl-5-trifluoromethyloxazole-4-carboxamide as Potent Diacylglycerol Acyltransferase-1 Inhibitors for the Potential Treatment of Obesity and Diabetes

2011 Journal of Medicinal Chemistry
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Derives spiro azacycliques

2010
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Derives de piperidine et leur utilisation pour le traitement de l'obesite, des diabetes, de la dislipidemie, et de l'atherosclerose

2010
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PEPCK complex with a GTP-competitive inhibitor

2007
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Fatty acid modulators for the treatment of diabesity

2007 Drug Discovery Today: Therapeutic Strategies
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Modified 3-alkyl-1,8-dibenzylxanthines as GTP-competitive inhibitors of phosphoenolpyruvate carboxykinase

2003 Bioorganic & Medicinal Chemistry Letters
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PEPCK complex with PEP

2002
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Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.

2002 Journal of Molecular Biology
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PEPCK complex with nonhydrolyzable GTP analog, native data

2002
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