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Daniel John Russell

AstraZeneca

14

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193

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Design, Synthesis, and Biological Activity of Substrate Competitive SMYD2 Inhibitors.

2016 Journal of Medicinal Chemistry
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Towards the next generation of dual Bcl-2/Bcl-xL inhibitors.

2014 Bioorganic & Medicinal Chemistry Letters
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Abstract B100: Structure-based design of AZ7732 a novel in vivo active beta-alanine-derived pan-IAP inhibitor.

2013 Molecular Cancer Therapeutics
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Abstract 2461: Design and synthesis of AZD3463, a novel orally bioavailable dual ALK and IGF1R inhibitor, inhibits growth of crizotinib resistance cell lines with multiple mechanisms of acquired resistance.

2013 Cancer Research
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Abstract 3910: Lead optimization of a series of 5-aminopyrazol-imidazopyridine compounds as potent anaplastic lymphoma kinase inhibitors active against clinically relevant ALK mutations

2012 Cancer Research
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Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization

2012 ACS Medicinal Chemistry Letters
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Discovery of novel hedgehog antagonists from cell-based screening: Isosteric modification of p38 bisamides as potent inhibitors of SMO

2012 Bioorganic & Medicinal Chemistry Letters
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Abstract 2916: Discovery of pyrazolimidazopyridine compounds as potent in vitro and in vivo anaplastic lymphoma kinase inhibitors

2012 Cancer Research
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Enantiomers of fused heterocycles selected and uses thereof

2005
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Structural Analysis and Optimization of NK1 Receptor Antagonists through Modulation of Atropisomer Interconversion Properties

2004 Journal of Medicinal Chemistry
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