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Dan Widzowski

AstraZeneca

13

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199

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Pharmacological Inhibition of PARP6 Triggers Multipolar Spindle Formation and Elicits Therapeutic Effects in Breast Cancer

2018 Cancer Research
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Abstract 919: AZD3463, a novel ALK/IGF1R inhibitor, overcomes multiple mechanisms of acquired resistance to crizotinib.

2013 Cancer Research
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Contrasting pharmacodynamic requirements of disease models revealed through characterization of a novel and selective M1 agonist

2013 The FASEB Journal
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Abstract 2461: Design and synthesis of AZD3463, a novel orally bioavailable dual ALK and IGF1R inhibitor, inhibits growth of crizotinib resistance cell lines with multiple mechanisms of acquired resistance.

2013 Cancer Research
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Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist

2011 Journal of Pharmacology and Experimental Therapeutics
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Absence of direct effects on the dopamine D2 receptor by mGluR2/3‐selective receptor agonists LY 354,740 and LY 379,268

2011 Synapse
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D2 receptor occupancy in conscious rat brain is not significantly distinguished with [3H]‐MNPA, [3H]‐(+)‐PHNO, and [3H]‐raclopride

2010 Synapse
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Dibenzothiazepinderivat and uses thereof

2009
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Selective α7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

2009 Biochemical Pharmacology
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Citations (89)