A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts

Mika Endo,Masanori Miwa,Masako Ura,Hiromi Tanimura,Kenji Taniguchi,Yoko Miyazaki,Jun Ohwada,Masao Tsukazaki,Satoshi Niizuma,Takeshi Murata,Sawako Ozawa,Hitomi Suda,Kotaro Ogawa,Eitaro Nanba,Shunsuke Nagao,Nobuo Shimma,Hisafumi Yamada-Okabe

A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts

2010

Mika Endo
Masanori Miwa
Masako Ura
Hiromi Tanimura
Kenji Taniguchi
Yoko Miyazaki
Jun Ohwada
Masao Tsukazaki
Satoshi Niizuma
Takeshi Murata
Sawako Ozawa
Hitomi Suda
Kotaro Ogawa
Eitaro Nanba
Shunsuke Nagao
Nobuo Shimma
Hisafumi Yamada-Okabe

Purpose Identification of a novel topoisomerase I inhibitor which shows superior efficacy and less individual variation than irinotecan hydrochloride (CPT-11).

Keywords:

Topoisomerase
Biochemistry
Topoisomerase-I Inhibitor
Abcg2
Irinotecan
Prodrug
Camptothecin
Pharmacology
Transplantation
Medicine
Irinotecan Hydrochloride

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations