TWO CASES OF ALLERGIC BRONCHOPULMONARY MYCOSIS

We present two cases of allergic bronchopulmonary aspergillosis or allergic bronchopulmonary penicilliosis. The first cas was a 15 year-old male with bronchial asthma. Chest roentgenogram showed an infiltration shadow in the bilateral upper lung fields, predominantly in the right upper lobe. Total serum IgE was 39000U/ml, RAST score to Aspergillus was 3, and peripheral blood eosinophil counts were 4984/μl. Type I skin reaction against Aspergillus was positive. Bronchoscopy showed mucoid impaction and Aspergillus grew in sputum cultures. Precipitating antibodies to Aspergillus were positive (16×) After corticosteroid administration, the symtoms and abnormal findings of chest roentgenogram were improved remarkably.The second case was all year-old male, who also had bronchial asthma. The chest roentgenogram showed total atelectasis of right lung field and mediastinum deviated towards the right. Total serum IgE was 975U/ml, RAST score to Penicillium was 2 and peripheral blood eosinophil counts were 584/μl. The type I skin reaction against Penicillium was positive. Bronchoscopy showed mucoid impaction, accompanied with positive fungus culture for Penicillium species. After corticosteroid administration, those symptoms and abnormal findings of chest roentgenogram were improved for a short while.