Journal Article Immunohistochemical Progesterone Receptor Assay: Measurement by Image Analysis Get access Nafissa El-Badawy, M.D., Nafissa El-Badawy, M.D. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia. Address reprint requests to Dr. Cohen: Anatomic Pathology, Emory University, 1364 Clifton Road, NE, Atlanta, Georgia 30322. Search for other works by this author on: Oxford Academic Google Scholar Cynthia Cohen, M.D., Cynthia Cohen, M.D. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia. Search for other works by this author on: Oxford Academic Google Scholar Patricia B. Derose, MT(ASCP)SH, Patricia B. Derose, MT(ASCP)SH Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia. Search for other works by this author on: Oxford Academic Google Scholar Irene J. Check, PH.D., Irene J. Check, PH.D. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia. Search for other works by this author on: Oxford Academic Google Scholar Demetrios Sgoutas, PH.D. Demetrios Sgoutas, PH.D. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia. Search for other works by this author on: Oxford Academic Google Scholar American Journal of Clinical Pathology, Volume 96, Issue 6, 1 December 1991, Pages 704–710, https://doi.org/10.1093/ajcp/96.6.704 Published: 01 December 1991 Article history Received: 15 December 1989 Accepted: 15 January 1991 Published: 01 December 1991
ABSTRACT An awareness of the protective roll of n‐3 polyunsaturated fatty acids against development of cardiovascular disease has prompted the promotion of fish consumption. It is assumed that those fish rich in polyunsaturated fat and particularly those having high ratios of n‐3 to n‐6 polyunsaturated fatty acids would confer the most benefit. The total fat and fatty acid compositional data are reported herein for 41 different species of fish that are mostly found in the coastal waters of the Eastern United States.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of geometry and position of ethylenic bond upon acyl coenzyme A-cholesterol-O-acyltransferaseDemetrios S. SgoutasCite this: Biochemistry 1970, 9, 8, 1826–1833Publication Date (Print):April 1, 1970Publication History Published online1 May 2002Published inissue 1 April 1970https://pubs.acs.org/doi/10.1021/bi00810a024https://doi.org/10.1021/bi00810a024research-articleACS PublicationsRequest reuse permissionsArticle Views50Altmetric-Citations50LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Weanling male Sprague-Dawley rats were maintained on a vitamin A (retinol)-deficient retinoic acid-supplemented diet for a period of 8 to 14 weeks. After 10 weeks, Leydig cell-enriched preparations from vitamin A-deficient animals had 45% fewer gonadotropin receptors for human luteinizing hormone (hLH). Testicular slices from vitamin A-deficient animals demonstrated decreased formation of adenosine 3′5′-monophosphate (cyclic AMP) and decreased testosterone content in response to hLH stimulation compared to vitamin A-supplemented rats (P < 0.01). Our findings suggest that changes which cause hyporesponsiveness in testosterone production from vitamin A-deficient rats can be attributed to a reduction in gonadotropin testicular receptors for hLH and a decreased cyclic AMP production. Testicular morphology was not altered during the first 10 weeks of the experiment, although, after 14 weeks on the experimental diet there was marked degeneration of tubules, cessation of spermatogenesis, and testicular atrophy.
Linoleic-1-C14 acid was rapidly incorporated into the liver lipids of both control and carbon tetrachloride treated rats. Twenty minutes after the injection, a pronounced fall in incorporation into phospha-tidyl ethanolamine with a concurrent rise in incorporation into cardiolipin and phospha-tidyl choline fractions was observed in the degenerating liver. The increased incorporation of radioactivity into cardiolipin and phos-phatidyl choline was reflected in an increased content of linoleic acid in these phospho-lipids but not in phosphatidyl ethanolamine. These results sugested the existence of separate pools of linoleic acid for incorporation into individual phospholipids.
