<p>Plants are natural products responsible for many biological activities. It is quite common to use plants that attract attention with their nutritive properties within the scope of complementary medicine. <em>Matricaria</em> species, which have naturally distributed, are among the plants used in traditional medicine. Revealing the biological activities of plants is very important in terms of their potential use. In this study, the usage areas, chemical contents and biological activities of <em>Matricaria </em>species reported in the literature were compiled. According to the findings, it was seen that it was used for health and cosmetic purposes. In addition, it has been observed that <em>Matricaria </em>species have biological activities such as antioxidant, antimicrobial and anticancer. It was observed that the dominant compounds from different <em>Matricaria </em>species were 1,5-Bis (dicyclohexylphosphino)-pentane (3.95-44.7%) and &alpha;-bisabolol (2.2-56.86%). According to the literature data, <em>Matricaria </em>species are an important natural resource. As a result, it is predicted that <em>Matricaria </em>species may be an important source in pharmacological studies.</p> <p>&nbsp;</p>
Since prehistoric times, humans have relied on plants for a wide variety of needs, including sustenance, shelter, thermal regulation, and medical treatment. Plants are significant organics because of the many ways they may be put to use. The white radish (Raphanus raphanistrum subsp. sativus (L.) Domin) was tested for its antioxidant and antibacterial properties, as were its tuber and aerial portions. A soxhlet was used to extract ethanol from plant material. The antioxidant and oxidant capacities were tested with the use of Rel Assay TAS and TOS kits. The agar dilution technique was used to test for antimicrobial activity against the bacteria and fungus included in the experiment. As a result of the studies, the TAS value of the tuber extract of the plant was measured as 6.698±0.187, the TOS value as 5.609±0.245 and the OSI value as 0.084±0.002. The TAS value of the herbal aerial parts extract was 4.689±0.223, the TOS value was 3.746±0.128, and the OSI value was 0.080±0.003. Inhibition of tuber extract was observed at concentrations varying between 25-100 against bacterial strains and 200 µg/mL against fungal strains. Aerial parts extract showed inhibition against bacterial strains at concentrations varying between 100-200 and against fungus strains at concentrations ranging from 200-400 µg/mL. As a result, it was determined that the white radish plant has significant antioxidant and antimicrobial activity.
Plants have been used for many purposes in different communities. Plants used in alternative medicine since ancient times have been the main material in the treatment of many diseases. In this context, it is very important to determine the biological potential of plants. In our study, total antioxidant status, total oxidant status, oxidative stress index and DPPH free radical scavenging activity of Euphorbia eriophora Boiss. were determined. The aerial parts of the plant were extracted with ethanol in a Soxhlet device. TAS, TOS and OSI values of the plant extract were determined using Rel Assay kits. In addition, the free radical scavenging activity of the plant extract was measured by the DPPH method. As a result of the studies, the TAS value of the plant extract was 5.390±0.227, the TOS value was 20.971±0.348, and the OSI value was 0.390±0.014. The DPPH activity of the plant extract was determined to have an inhibition value of 68.721±1.694% at 2 mg/mL concentration. As a result, in our study, it was determined that E. eriophora has antioxidant potential and can be used as a natural antioxidant agent in this context.
Objective: Plants are preferred for biological effect. It is a natural resource used in the field of alternative medicine due to its biological effect. In our study, the total oxidant status (TOS) and oxidative stress index (OSI) and total antioxidant status (TAS) of Viola odorata L. species were detected. In addition, antimicrobial and antiproliferative effect of species was detected. Material and Method: The some parts of the species were used with the help of a soxhlet equipment, and ethanol was preferred as a solvent. TOS, OSI and TAS capacitiy were detected using Rel Assay kits. Agar dilution method was preferred to determine antimicrobial effect against bacteria and fungi. Lung cancer cell line (A549) was used to find out the antiproliferative effect by MTT assay. Result and Discussion: Consequently, the studies, the TAS capacitiy of V. odorata extract was detected as 6.752±0.139, the TOS capacitiy as 7.886±0.224 and the OSI capacitiy as 0.117±0.001. V. odorata extracts were determined to be influential against standard bacteria at 25-100 μg/ml intensiy and against fungi at 100-200 μg/ml intensiy. It was detected that the antiproliferative effect of V. odorata extract increased depending on the extract intensiy and showed strong effects. Consequently, it has been detected that V. odorata has important biological effects and in the pharmaceutical industry, it can be preferred after certain stages.
Plants are unique resources utilised by various communities within natural products. The use of plants within the scope of traditional medicine has significant contributions in the treatment of diseases. The investigation of the potential therapeutic effects of plants within this scope is important in terms of their utilisation as natural resources. In this study, a compilation of research conducted on Cuminum species in the literature is presented. Within this context, the utilisation areas, general characteristics, biological activities, and chemical contents of Cuminum species have been compiled. According to the literature, it has been determined that spices are particularly utilised in the fields of cosmetics, disease management, and culinary arts. Furthermore, it has been observed that they are significant sources in terms of anticancer, antioxidant, and antimicrobial properties. It has been observed that the compound with the highest concentration in its constituents is cuminlaldehyde (19.9-64.31%). When necessary studies and procedures are applied based on literature data, Cuminum species serve as important natural resources in pharmacological designs.
The treatment of microbial infections has proven challenging for humans in recent years. Synthetic medications, such as antimicrobial agents, are used for treating these infections. Antimicrobials derived from natural sources have gained popularity as an alternative to manufactured medications due to their lack of adverse effects. Plants, which play a significant role in this setting, have historically served as a reliable natural defence against several pathogens. In this study, studies on plants used against viral diseases are mentioned. Studies on viruses that cause disease have been compiled in the literature. According to the findings, it has been reported in the literature that many different plant species are effective against herpes simplex virus (HSV-1, HSV-2), human immunodeficiency virus (HIV), influenza virus (A, B) and parainfluenza, Poliovirus, Astrovirus, Parvovirus, Sindbis virus (SINV), Feline calicivirus (FCV), Rhinovirus, Echovirus, Rotavirus, Bovine alphaherpesvirus 1 (BoHV-1), Reovirus, Vaccinia virus (VACV), Cardiovirus A (Encephalomyocarditis virus; EMCV), Coxsackie virus, Semliki forest, Measles virus, Newcastle disease virus (NDV), Coronavirus, Adenovirus (ADV-3, ADV-5, ADV-8, ADV -11), Canine distemper virus (CDV), Lumpy skin disease virus (LSDV), Hepatitis A, B, C virus and Enterovirus. To combat viruses, plants can be considered a potentially invaluable natural resource.
Plants are important natural materials used in complementary medicine. In this study, antioxidant and antimicrobial activities of Scorzonera papposa DC. collected from Duhok (Iraq) and Gaziantep (Turkey) regions were determined. Extracts of aerial parts and roots of the plant with ethanol were obtained. Antioxidant and oxidant potentials were determined by using Rel Assay Diagnostics kits. Antimicrobial activities were tested against bacteria and fungus strains using the agar dilution method. In our study, it was determined that S. papposa has important antioxidant activity. Also, It was found that extracts of plant parts were effective at 50-800 µg/mL concentrations. As a result, it was determined that S. papposa could be a natural antioxidant and antimicrobial agent that can be used in complementary medicine.
Abstract In this study, antioxidant, oxidant, antimicrobial, and antiproliferative activities of Asparagus acutifolius L. and Asparagus officinalis L., known for their nutritional properties, were determined. In this context, methanol (MeOH) and dichloromethane (DCM) extracts of plants were obtained. Total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were determined using Rel Assay kits. Antimicrobial activities of plant extracts were determined against the test microorganisms using the agar dilution method. Antiproliferative activity was tested on the lung cancer cell line A549. As a result of the studies, it has been determined that the plant species have high antioxidant potential. In addition, it was observed that the antifungal potentials of plant extracts are high. Antiproliferative activity was determined to be at high level in both plant species. As a result, it has been determined that A. acutifolius and A. officinalis have medical potential and can be used as natural agents in pharmacological designs.
Amaç: Alternatif tıp, insanlık tarihinde birçok hastalıkla mücadelede önemli bir yere sahiptir. Bu çalışmada Glycyrrhiza glabra L.'nin biyolojik aktivitesi araştırıldı. Gereç ve Yöntem: Bitkinin kök kısımları etanol ile ekstrakte edildi. Antioksidan ve oksidan potansiyelleri Rel Assay kitleri kullanılarak belirlendi. Antimikrobiyal aktivite, agar seyreltme yöntemi kullanılarak standart bakteri ve mantar suşlarına karşı test edildi. Antiproliferatif aktivite, Lung Carcinoma Cell Line'a (A549) karşı MTT testi ile belirlendi. Sonuç ve Tartışma: Çalışmalar sonucunda bitkinin TAS değeri 8.770±0.171, TOS değeri 14.590±0.191 ve OSI değeri 0.167±0.005 olarak ölçülmüştür. Bitki ekstraktının 50-200 µg/mL konsantrasyon aralığında standart bakteri ve mantar suşlarına karşı inhibisyonu gözlemlendi. Ayrıca bitki ekstraktının konsantrasyon artışına bağlı olarak güçlü antiproliferatif aktivite gösterdiği belirlendi. Bu çalışmalar sonucunda G. glabra'nın önemli bir doğal antioksidan, antimikrobiyal ve antikanser ajanı olarak kullanılabileceği belirlenmiştir.
The present study was aimed to evaluate the protective effect of ethanolic extract of Ipomoea staphylina leaves against cadmium-induced cardiotoxicity in rats. Rats were segregated into four groups which included normal control, cadmium treated, Cd+ Ipomoea staphylina (200 mg/kg) treated, and Cd+ Ipomoea staphylina (400 mg/kg) treated. The cadmium treatment resulted in a significant increase in the activities of lactate dehydrogenase, creatine phosphokinase, serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase. Also, a significant increase in the levels of cholesterol, triglycerides, and low-density lipoprotein was noticed after cadmium treatment. On the other hand, high-density lipoprotein was significantly decreased following cadmium treatment. A significant decline in the activity of antioxidant enzymes was observed in cadmium intoxicated rats. Moreover, cadmium intoxicated rats resulted in significant increase in the levels of proinflammatory cytokines such as tumor necrosis factor alpha, interleukin 1 beta, and nitric oxide in the cardiac tissue. Supplementation of Ipomoea staphylina leaves extract to cadmium treated rats reversed most of the indices. The extract (400 mg/kg) revealed better protective effects by decreasing the activities of lactate dehydrogenase, creatine phosphokinase, serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase and improving the lipid profile. Besides, the extract also significantly improved the antioxidant enzymes activity and decreased the level of tumor necrosis factor alpha, interleukin 1 beta, and nitric oxide. Further, the histopathological study of heart supported the protective effects of Ipomoea staphylina leaves extract. The study, therefore, concludes that Ipomoea staphylina leaves extract holds a strong protective effect against cadmium-induced cardiotoxicity in rats.
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