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David W. Schulz

Pfizer

36

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Low efficacy partial agonists of the α4β2 nicotinic acetylcholine receptor (nAChR). Does functional efficacy govern in vivo response

2009 Biochemical Pharmacology
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2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists.

2008 Journal of Medicinal Chemistry
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Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists.

2008 Journal of Medicinal Chemistry
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Pharmacological profile of the α4β2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

2007 Neuropharmacology
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The pharmacology of CP-154,526, a non-peptide antagonist of the CRH1 receptor: a review.

2006 Cns Drug Reviews
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D1 Dopamine Receptors in the Amygdala Exhibit Unique Properties

2006 Annals of the New York Academy of Sciences
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3,5-Bicyclic aryl piperidines: A novel class of α4β2 neuronal nicotinic receptor partial agonists for smoking cessation

2005 Bioorganic & Medicinal Chemistry Letters
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Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation

2005 Journal of Medicinal Chemistry
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New paradigms, animal models may lift antidepressant research

2004 Nature Medicine
- David W. Schulz
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Synthesis and oral efficacy of a 4-(butylethylamino)pyrrolo[2,3-d]pyrimidine: a centrally active corticotropin-releasing factor1 receptor antagonist.

1997 Journal of Medicinal Chemistry
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Citations (112)