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Kelly M. Treonze

Merck & Co.

7

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Fibrinopeptide A±360: A Biomarker Of Neutrophil Elastase Activity

2010 ATS | American Thoracic Society International Conference
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Discovery of N-{N-[(3-cyanobenzene) sulfonyl]-4(R)-(3,3-difluoropiperidin-1-yl)-(l)-prolyl}-4-[(3',5'-dichloro-isonicotinoyl) amino]-(l)-phenylalanine (MK-0617), a highly potent and orally active VLA-4 antagonist.

2009 Bioorganic & Medicinal Chemistry Letters
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Characterization of α4β1 (CD49d/CD29) on equine leukocytes: potential utility of a potent α4β1 (CD49d/CD29) receptor antagonist in the treatment of equine heaves (recurrent airway obstruction).

2009 Veterinary Immunology and Immunopathology
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Discovery of N-{N-[(3-cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(L)-prolyl}-4-[(3',5'-dichloroisonicotinoyl) amino]-(L)-phenylalanine (MK-0668), an extremely potent and orally active antagonist of very late antigen-4.

2009 Journal of Medicinal Chemistry
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Small Molecule Inhibitor of Neutrophil Elastase Restores Impaired Production of Human Myeloid Cells Observed in Severe Congenital Neutropenia.

2007 Blood
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