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Jacques Moisan

MedImmune

13

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132

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Discovery of LYC-55716: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor-γ (RORγ) Agonist for Use in Treating Cancer.

2021 Journal of Medicinal Chemistry
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In vitro priming of adoptively transferred T cells with a RORγ agonist confers durable memory and stemness in vivo

2018 Cancer Research
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A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

2017 Journal of Immunology
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A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors

2016 Cancer Research
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Abstract 4273: RORγ agonists as a novel immunotherapy approach for cancer

2015 Cancer Research
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RORgamma agonists enhance survival and memory of type 17 T cells and improve anti-tumor activity

2015 Journal for ImmunoTherapy of Cancer
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Novel, synthetic RORgamma agonist compounds as a potential anti-cancer approach

2014 F1000Research
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Novel synthetic RORγ agonist compounds as a potential anti-tumor therapeutic approach

2014 Journal for ImmunoTherapy of Cancer
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Decay of excited nuclei produced in Kr78,82+Ca40 reactions at 5.5 MeV/nucleon

2011 Physical Review C
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Citations (37)