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Neil Benson

Pfizer

35

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Application of Pharmacokinetic and Pharmacodynamic Modeling of Biomarkers of Efficacy in Translational Research

2019
- Neil Benson
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Use of mathematics to guide target selection in systems pharmacology; application to receptor tyrosine kinase (RTK) pathways

2017 European Journal of Pharmaceutical Sciences
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Topics in Mathematical Pharmacology

2016 Journal of Dynamics and Differential Equations
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Prediction of long-term treatment outcome in HCV following 24 day PEG-IFN alpha-2b therapy using population pharmacokinetic-pharmacodynamic mixture modeling and classification analysis.

2015 Journal of Theoretical Biology
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A Systems Pharmacology Perspective on the Clinical Development of Fatty Acid Amide Hydrolase Inhibitors for Pain

2014
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Model-based drug development: a rational approach to efficiently accelerate drug development.

2013 Clinical Pharmacology & Therapeutics
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Modeling of celiac disease immune response and the therapeutic effect of potential drugs

2013 BMC Systems Biology
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Systems pharmacology of the nerve growth factor pathway: use of a systems biology model for the identification of key drug targets using sensitivity analysis and the integration of physiology and pharmacology.

2013 Interface Focus
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The discovery of a novel prototype small molecule TLR7 agonist for the treatment of hepatitis C virus infection

2011 MedChemComm
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Pharmacokinetic-Pharmacodynamic Modeling of Alpha Interferon Response Induced by a Toll-Like 7 Receptor Agonist in Mice

2010 Antimicrobial Agents and Chemotherapy
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Citations (11)