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David C. Pryde

Pfizer

83

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1738

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The discovery of potent small molecule activators of human STING.

2021 European Journal of Medicinal Chemistry
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CHAPTER 12:Aldehyde and Xanthine Oxidase Metabolism

2021
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G10 is a direct activator of human STING.

2020 PLOS ONE
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Valproic acid interactions with the NavMs voltage-gated sodium channel.

2019 Proceedings of the National Academy of Sciences of the United States of America
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A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.

2019 Science
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An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes.

2018 Structure
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The discovery of a potent Nav1.3 inhibitor with good oral pharmacokinetics

2017 MedChemComm
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Site-selective Suzuki–Miyaura coupling of heteroaryl halides – understanding the trends for pharmaceutically important classes††Electronic supplementary information (ESI) available: Notes on mixed halide–triflate heterocycles and details of the Pfizer RKB and CAS Scifinder® searches. See DOI: 10.10

2017
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Site-selective Suzuki–Miyaura coupling of heteroaryl halides – understanding the trends for pharmaceutically important classes

2017 Chemical Science
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Corrigendum to “Investigation of the structure activity relationship of flufenamic acid derivatives at the human TRESK channel K2P18.1” [Bioorg. Med. Chem. Lett. 26 (2016) 4919–4924]

2017 Bioorganic & Medicinal Chemistry Letters
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