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Jie Chen

Amgen

9

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169

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Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors

2016 Journal of Medicinal Chemistry
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Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.

2016 ACS Medicinal Chemistry Letters
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Abstract 5398: In vivo development of pan-Pim kinase small molecule inhibitors

2015 Cancer Research
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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept

2014 Journal of Medicinal Chemistry
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Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 4. Exploration of a novel binding pocket.

2014 Journal of Medicinal Chemistry
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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 3. Structure–Activity Relationships within the Aryl Carbinol Region of the N-Arylsulfonamido-N′-arylpiperazine Series

2014 Journal of Medicinal Chemistry
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