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Anthony M. Giannetti

Genentech

19

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1257

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Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling.

2014 Cancer Cell
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Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors.

2014 Bioorganic & Medicinal Chemistry Letters
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Tailoring small molecules for an allosteric site on procaspase-6.

2014 ChemMedChem
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Inside Cover: Tailoring Small Molecules for an Allosteric Site on Procaspase‐6 (ChemMedChem 1/2014)

2014 ChemMedChem
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Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.

2014 Bioorganic & Medicinal Chemistry Letters
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Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).

2014 Bioorganic & Medicinal Chemistry Letters
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Internal motions prime cIAP1 for rapid activation

2014 Nature Structural & Molecular Biology
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Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase.

2013 Bioorganic & Medicinal Chemistry Letters
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Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase.

2013 Bioorganic & Medicinal Chemistry Letters
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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

2012 Proceedings of the National Academy of Sciences of the United States of America
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