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Stephen Fawell

Novartis

11

Papers

1690

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Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T-cell lymphoma models: Defining molecular mechanisms of resistance.

2010 International Journal of Cancer
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Abstract 138: Therapeutic targeting of inhibitor of apoptosis proteins

2010 Cancer Research
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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

2009 Nature
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Mechanism of action studies using a Smac mimetic reveal positive and negative roles of inhibitor of apoptosis proteins (IAPs) in TNFα signaling

2008 Cancer Research
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161 POSTER Potent anticancer activity of panobinostat (LBH589) in models of hormone-refractory prostate cancer (HRPC): targeting the androgen receptor

2008 Ejc Supplements
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151 POSTER Efficacy of panobinostat (LBH589) in lung cancer: potent anticancer activity in both in vitro and in vivo tumor models

2008 Ejc Supplements
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Efficacy of Panobinostat (LBH589) in CTCL Cell Lines and a Murine Xenograft Model: Defining Molecular Pathways of Panobinostat Activity in CTCL.

2007 Blood
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Efficacy of Panobinostat (LBH589) in Multiple Myeloma Cell Lines and In Vivo Mouse Model: Tumor-Specific Cytotoxicity and Protection of Bone Integrity in Multiple Myeloma.

2007 Blood
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Citations (2)