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Toshiyuki Maki
Toshiyuki Maki
Takeda Pharmaceutical Company
Monoacylglycerol lipase
Chemistry
Biochemistry
Trifluoromethyl
Organic chemistry
4
Papers
47
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Inhibition of MGAT2 modulates fat‐induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high fat diet
2019
FEBS Open Bio
Taisuke Mochida
Kazumi Take
Toshiyuki Maki
Masanori Nakakariya
Ryutaro Adachi
Kenjiro Sato
Tomoyuki Kitazaki
Shiro Takekawa
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Citations (2)
Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization
2016
PLOS ONE
Kazumi Take
Taisuke Mochida
Toshiyuki Maki
Yoshinori Satomi
Megumi Hirayama
Masanori Nakakariya
Nobuyuki Amano
Ryutaro Adachi
Kenjiro Sato
Tomoyuki Kitazaki
Shiro Takekawa
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Citations (12)
Discovery of a Novel Series of N-Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase-2 Inhibitors
2015
Journal of Medicinal Chemistry
Kenjiro Sato
Hiroki Takahagi
Takeshi Yoshikawa
Shinji Morimoto
Takafumi Takai
Kousuke Hidaka
Masahiro Kamaura
Osamu Kubo
Ryutaro Adachi
Tsuyoshi Ishii
Toshiyuki Maki
Taisuke Mochida
Shiro Takekawa
Masanori Nakakariya
Nobuyuki Amano
Tomoyuki Kitazaki
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Citations (25)
Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities
2015
Bioorganic & Medicinal Chemistry
Kenjiro Sato
Hiroki Takahagi
Osamu Kubo
Kousuke Hidaka
Takeshi Yoshikawa
Masahiro Kamaura
Masanori Nakakariya
Nobuyuki Amano
Ryutaro Adachi
Toshiyuki Maki
Kazumi Take
Shiro Takekawa
Tomoyuki Kitazaki
Tsuyoshi Maekawa
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Citations (8)
1