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Carole L. Yauk

Health Canada
University of Ottawa

233

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6318

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Potency ranking of per- and polyfluoroalkyl substances using high-throughput transcriptomic analysis of human liver spheroids.

2021 Toxicological Sciences
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A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures.

2021 Frontiers in Public Health
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High-throughput transcriptomic analysis of human primary hepatocyte spheroids exposed to per- and polyfluoroalkyl substances (PFAS) as a platform for relative potency characterization.

2021 Toxicological Sciences
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Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology

2021 Regulatory Toxicology and Pharmacology
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A Transcriptomic Dataset Used to Derive Biomarkers of Chemically Induced Histone Deacetylase Inhibition (HDACi) in Human TK6 Cells

2021 Data in Brief
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Prolonged low-dose dioxin exposure impairs metabolic adaptability to high-fat diet feeding in female but not male mice.

2021 Endocrinology
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Adverse Outcome Pathway on Cyp2E1 activation leading to liver cancer

2021
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Transcriptomics and relative potency assessments using bench mark dose of bisphenol a, bisphenol S, bisphenol F, and 3,3',5,5'-Tetrabromobisphenol a in H9 human embryonic stem cells

2021 Toxicology in Vitro
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Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells.

2021 Archives of Toxicology
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The 28 + 28 day design is an effective sampling time for analyzing mutant frequencies in rapidly proliferating tissues of MutaMouse animals

2021 Archives of Toxicology
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