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Abdul Mutlib

Pfizer

36

Papers

1903

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Evaluation of absorption, distribution, metabolism, and excretion of [14C]-rucaparib, a poly(ADP-ribose) polymerase inhibitor, in patients with advanced solid tumors

2019 Investigational New Drugs
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Characterization of HKI-272 Covalent Binding to Human Serum Albumin

2010 Drug Metabolism and Disposition
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Bioactivation of lamotrigine in vivo in rat and in vitro in human liver microsomes, hepatocytes, and epidermal keratinocytes: characterization of thioether conjugates by liquid chromatography/mass spectrometry and high field nuclear magnetic resonance spectroscopy.

2010 Chemical Research in Toxicology
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Characterization of Cytochrome P450-Mediated Bioactivation of a Compound Containing the Chemical Scaffold, 4,5-Dihydropyrazole-1-carboxylic acid-(4-chlorophenyl amide), to a Chemically Reactive p-Chlorophenyl Isocyanate Intermediate in Human Liver Microsomes

2009 Chemical Research in Toxicology
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Obtaining exposures of metabolites in preclinical species through plasma pooling and quantitative NMR: addressing metabolites in safety testing (MIST) guidance without using radiolabeled compounds and chemically synthesized metabolite standards.

2009 Chemical Research in Toxicology
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Nuclear magnetic resonance spectroscopy as a quantitative tool to determine the concentrations of biologically produced metabolites: implications in metabolites in safety testing.

2009 Chemical Research in Toxicology
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Application of Stable Isotope-Labeled Compounds in Metabolism and in Metabolism-Mediated Toxicity Studies

2008 Chemical Research in Toxicology
- Abdul Mutlib
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Liquid chromatography/mass spectrometry determination of endogenous plasma acetyl and palmitoyl carnitines as potential biomarkers of β-oxidation in mice

2008 Rapid Communications in Mass Spectrometry
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Application of In-Line Liquid Chromatography-Accurate Radioisotope Counting-Mass Spectrometry (LC-ARC-MS) to Evaluate Metabolic Profile of [3H]-Mefenamic Acid in Rat Plasma

2007 Drug Metabolism Letters
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Rational design of 7-arylquinolines as non-competitive metabotropic glutamate receptor subtype 5 antagonists

2007 Bioorganic & Medicinal Chemistry Letters
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Citations (19)