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Kym N. Lowes

Walter and Eliza Hall Institute of Medical Research
University of Melbourne

38

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2159

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Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2.

2021 ACS Infectious Diseases
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Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity.

2021 Bioorganic Chemistry
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Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.

2021 European Journal of Medicinal Chemistry
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Basis for drug selectivity of plasmepsin IX and X inhibition for Plasmodium falciparum and vivax

2021
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Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3

2019 Cell Reports
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Colorectal Cancer Cell Line Proteomes are Representative of Primary Tumors and Predict Drug Sensitivity

2017 Gastroenterology
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Exploration of the P3 region of PEXEL peptidomimetics leads to a potent inhibitor of the Plasmodium protease, plasmepsin V.

2016 Bioorganic & Medicinal Chemistry
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A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

2015 Nature Communications
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Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy

2015 Science Translational Medicine
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Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes.

2015 Nature Structural & Molecular Biology
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Citations (67)