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Zhuyan Guo

Schering-Plough

37

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661

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Basis for drug selectivity of plasmepsin IX and X inhibition for Plasmodium falciparum and vivax

2021
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Abstract 1377: Identification and validation of WRN as a novel synthetic lethality target in context of microsatellite instability

2020
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INHIBITEURS PDE9 DE PYRAZOLOPYRIMIDINE

2018
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The importance of protonation and tautomerization in relative binding affinity prediction: a comparison of AMBER TI and Schrödinger FEP.

2016 Journal of Computer-aided Molecular Design
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Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor.

2016 ACS Medicinal Chemistry Letters
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Generation of a chimeric hepatitis C replicon encoding a genotype-6a NS3 protease and assessment of boceprevir (SCH503034) sensitivity and drug-associated mutations

2014 Antiviral Therapy
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Novel Quinoline-Based P2-P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease Inhibitors.

2014 ACS Medicinal Chemistry Letters
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Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

2014 ACS Medicinal Chemistry Letters
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Pivotal Role of an Aliphatic Side Chain in the Development of an HDM2 Inhibitor

2014 ACS Medicinal Chemistry Letters
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The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir®: A change in direction in the search for a second generation HCV NS3 protease inhibitor

2010 Bioorganic & Medicinal Chemistry Letters
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Citations (21)