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Yoshihide Tomata

Takeda Pharmaceutical Company

13

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127

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Design and Synthesis of Conformationally Constrained RORγt Inverse Agonists

2019 ChemMedChem
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Identification of novel quinazolinedione derivatives as RORγt inverse agonist

2017 Bioorganic & Medicinal Chemistry
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Parallel fluorescent probe synthesis based on the large-scale preparation of BODIPY FL propionic acid

2017 Bioorganic & Medicinal Chemistry Letters
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Facile Preparation of 3-Substituted-2,6-difluoropyridines: Application to the Synthesis of 2,3,6-Trisubstituted Pyridines.

2016 ChemInform
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Facile preparation of 3-substituted-2,6-difluoropyridines: application to the synthesis of 2,3,6-trisubstituted pyridines

2015 Tetrahedron Letters
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Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators.

2015 Bioorganic & Medicinal Chemistry Letters
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Discovery of Spiropiperidine-Based Potent and Selective Orexin-2 Receptor Antagonists.

2012 ChemInform
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Discovery of potent, selective, orally active benzoxazepine-based Orexin-2 receptor antagonists.

2011 Bioorganic & Medicinal Chemistry Letters
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Discovery of spiropiperidine-based potent and selective Orexin-2 receptor antagonists.

2011 Bioorganic & Medicinal Chemistry Letters
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