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Christophe Michoud

Hoffmann-La Roche

18

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204

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Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): kinase profiling guided optimization of a 1,2,3-benzotriazole lead.

2013 Bioorganic & Medicinal Chemistry Letters
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Optimization of Benzodiazepinones as Selective Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain

2013 Journal of Medicinal Chemistry
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Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.

2013 Journal of Medicinal Chemistry
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Benzotriazole as modulators of kinases

2007
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Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors

2007 Bioorganic & Medicinal Chemistry Letters
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Design, synthesis and structure activity relationship within a series of pyrimidopyrimidine dual DKR/FGFR tyrosine kinase inhibitors.

2004 Cancer Research
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Pyrimido compounds with antiproliferative effect

2003
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Composes pyrimido presentant une activite anti-proliferative (ii)

2003
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Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1.

2000 Protein Engineering
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4,5-pyrazinoxindoles comme inhibiteurs de proteine kinase

1999
- Kin-Chun Luk
- Christophe Michoud
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