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Bruno Giethlen
Bruno Giethlen
Pharmacology
Allosteric modulator
Allosteric regulation
Metabotropic glutamate receptor 4
Structure–activity relationship
2
Papers
35
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Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs
2019
ACS Medicinal Chemistry Letters
Andrew John Harvey
Thomas Avery
Laurent Schaeffer
Christophe Joseph
Belinda Huff
Rajinder Singh
Christophe Morice
Bruno Giethlen
Anton Grishin
Carolyn Coles
Peter Kolesik
S. Wagner
Emile Andriambeloson
B. Huyard
E. Poiraud
Dharam Paul
S. O Connor
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Citations (13)
Discovery, Structure–Activity Relationship, and Antiparkinsonian Effect of a Potent and Brain-Penetrant Chemical Series of Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4
2017
Journal of Medicinal Chemistry
Delphine Charvin
Vincent Pomel
Millan Ortiz
Mélanie Frauli
Sophie Scheffler
Edith Steinberg
Luc Baron
Laurène Deshons
Rachel Rudigier
Delphine Thiarc
Christophe Morice
Baptiste Manteau
Stanislas Mayer
Danielle Graham
Bruno Giethlen
Nadia Brugger
Gaël Hédou
Francois Conquet
Stephan Schann
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Citations (22)
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