Metabotropic glutamate receptor 4

2914268934ENSG00000124493ENSMUSG00000063239Q14833Q68EF4NM_001256813NM_001256814NM_001282847NM_001013385NM_001291045NM_001360192NP_001269776NP_001013403NP_001277974NP_001347121Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of the metabotropic glutamate receptor family. Group III receptors are linked to the inhibition of the cyclic AMP cascade.Activation of GRM4 has potential therapeutic benefits in the treatment of parkinson's disease. Splice variant 'taste-GRM4' is involved in the perception of umami taste. This article incorporates text from the United States National Library of Medicine, which is in the public domain.