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AstraZeneca
Chemistry
Biochemistry
Cocrystal
RAR-related orphan receptor gamma
Bioavailability
4
Papers
35
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Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design
2018
Journal of Medicinal Chemistry
Frank Narjes
Yafeng Xue
Stefan Berg
Jesper Malmberg
Antonio Llinas
Roine I. Olsson
Johan Jirholt
Hanna Grindebacke
Agnes Leffler
Nafizal Hossain
Matti Lepistö
Linda Thunberg
Hanna Leek
A. Aagaard
Jane McPheat
Eva L. Hansson
E. Back
Stefan Tångefjord
Rongfeng Chen
Yao Xiong
Ge HongBin
Thomas Hansson
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Citations (21)
Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity
2018
Journal of Medicinal Chemistry
Patrik Johansson
Karin Kaspersson
Ian Gurrell
E. Back
Susanna Eketjäll
Clay W Scott
Gvido Cebers
Philip Thorne
Michael J. McKenzie
Haydn Beaton
Paul Davey
Karin Kolmodin
Jörg Holenz
Mark E. Duggan
Samantha Budd Haeberlein
Roland W. Bürli
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Citations (14)
Structure-based design leads to potent and orally bioavailable inverse agonists of ROR gamma t.
2018
Journal of Medicinal Chemistry
Frank Narjes
Yafeng Xue
S. von Berg
Jesper Malmberg
Antonio Llinas
Roine I. Olsson
Johan Jirholt
Hanna Grindebacke
Agnes Leffler
Nafizal Hossain
Matti Lepistö
Linda Thunberg
Hanna Leek
A. Aagaard
Jane McPheat
Eva L. Hansson
E. Back
Stefan Tångefjord
Rongfeng Chen
Yao Xiong
G. Hongbin
Thomas Hansson
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Identification and structural characterization of PDE10 fragment inhibitors
2013
Patrik Johansson
Jeffrey S. Albert
L. Spadola
Tomas Åkerud
E. Back
Per Hillertz
R. Horsefeld
Clay W Scott
N. Spear
Gaochao Tian
A. Tigerstrom
David Aharony
Stefan Geschwindner
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