author-photo

V. Santhakumar

Structural Genomics Consortium

25

Papers

227

Citations

Citation Trend

Filter By

Papers (16) Sort By

Journal Conference Others

Rational Design and Synthesis of Selective PRMT4 Inhibitors: a New Chemotype for Development of Cancer Therapeutics.

2021 ChemMedChem
Show All
- Source
- Cite
- Save
Citations (1)
Identification of a C2'-Fluorinated SAH Analogue

2020 Canadian Journal of Chemistry
Show All
- Source
- Cite
- Save
Citations (0)
Identification and Characterization of the First Fragment Hits for SETDB1 Tudor Domain

2019 bioRxiv
Show All
- Source
- Cite
- Save
Citations (0)
Identification and Characterization of the First Fragment Hits for SETDB1 Tudor Domain

2019 Bioorganic & Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (3)
Crystal structure of fragment 3-(3-Methoxy-2-quinoxalinyl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain

2018
Show All
- Source
- Cite
- Save
Citations (0)
Discovery and structure activity relationship of the first potent cryptosporidium FIKK kinase inhibitor

2017 Bioorganic & Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (11)
Crystal structure of fragment 3-(3-(pyridin-2-ylmethoxy)quinoxalin-2-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain

2017
Show All
- Source
- Cite
- Save
Citations (0)
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

2017 Nature Chemical Biology
Show All
- Source
- Cite
- Save
Citations (61)
Crystal structure of a low occupancy fragment candidate (N-(4-Methyl-1,3-thiazol-2-yl)propanamide) bound adjacent to the ubiquitin binding pocket of the HDAC6 zinc-finger domain

2016
Show All
- Source
- Cite
- Save
Citations (0)
SETDB1 in complex with an early stage, low affinity fragment candidate modelled at reduced occupancy into weak electron density

2016
Show All
- Source
- Cite
- Save
Citations (0)