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Johanna Flach

University of California, San Francisco

20

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2032

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Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.

2021 Journal of Experimental Medicine
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Destruction of a microtubule-bound MYC reservoir during mitosis contributes to vincristines anti-cancer activity.

2020 Molecular Cancer Research
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MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis

2016 Nature Communications
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Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis

2015 eLife
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Aberrant Hematopoietic Stem Cell Function in Mice Haploinsufficient for a 2 Mb Deletion of Chromosome 5A3 Syntenic to a Region of Human 7q22 Frequently Deleted in Myelodysplastic Syndromes

2014 Blood
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FOXO3A directs a protective autophagy program in haematopoietic stem cells.

2013 Nature
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Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche

2013 Cell Stem Cell
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Increased γH2AX Foci in Old Hematopoietic Stem Cells Are Independent of the DNA Damage Response and Linked to Inefficient DNA Replication/Transcription

2012 Blood
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An accumulation of cytogenetic and molecular genetic events characterizes the progression from MDS to secondary AML: an analysis of 38 paired samples analyzed by cytogenetics, molecular mutation analysis and SNP microarray profiling

2011 Leukemia
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Mutations of JAK2 and TET2, but not CBL are detectable in a high portion of patients with refractory anemia with ring sideroblasts and thrombocytosis.

2010 Haematologica
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Citations (42)