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Cynthia Serdikoff
Cynthia Serdikoff
Cephalon
Immunology
Janus kinase 2
Immune system
Proinflammatory cytokine
Tyrosine kinase
4
Papers
383
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A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5-A]Pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of Cep-33779.
2012
Journal of Medicinal Chemistry
Benjamin J. Dugan
Diane E. Gingrich
Eugen F. Mesaros
Karen L. Milkiewicz
Matthew A. Curry
Allison L. Zulli
Pawel Dobrzanski
Cynthia Serdikoff
Mahfuza Jan
Thelma S. Angeles
Mark S. Albom
Jennifer L. Mason
Lisa D. Aimone
Sheryl L. Meyer
Zeqi Huang
Kevin J. Wells-Knecht
Mark A. Ator
Bruce Ruggeri
Bruce D. Dorsey
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Citations (41)
A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis
2011
Arthritis Research & Therapy
Kristine L. Stump
Lily D. Lu
Pawel Dobrzanski
Cynthia Serdikoff
Diane E. Gingrich
Ben J Dugan
Thelma S. Angeles
Mark S. Albom
Mark A. Ator
Bruce D. Dorsey
Bruce Ruggeri
Matthew M. Seavey
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Citations (64)
Depletion of Autoreactive Plasma Cells and Treatment of Lupus Nephritis in Mice Using CEP-33779, a Novel, Orally Active, Selective Inhibitor of JAK2
2011
Journal of Immunology
Lily D. Lu
Kristine L. Stump
Nate H. Wallace
Pawel Dobrzanski
Cynthia Serdikoff
Diane E. Gingrich
Benjamin J. Dugan
Thelma S. Angeles
Mark S. Albom
Jennifer L. Mason
Mark A. Ator
Bruce D. Dorsey
Bruce Ruggeri
Matthew M. Seavey
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Citations (53)
Lestaurtinib (CEP701)is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders
2008
Blood
Elizabeth O. Hexner
Cynthia Serdikoff
Mahfuza Jan
Cezary R. Swider
Candy Robinson
Shi Yang
Thelma S. Angeles
Stephen G. Emerson
Martin Carroll
Bruce Ruggeri
Pawel Dobrzanski
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Citations (225)
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