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Natacha Novosad

Centre national de la recherche scientifique

8

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Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells

2017 Journal of Medicinal Chemistry
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Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A

2016 Future Medicinal Chemistry
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Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2’-deoxycytidine in human leukemic KG1 cells

2015 Oncotarget
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Design and synthesis of new non nucleoside inhibitors of DNMT3A.

2015 Bioorganic & Medicinal Chemistry
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Design, Synthesis and Biological Evaluation of 4‐Amino‐N‐(4‐aminophenyl)benzamide Analogues of Quinoline‐Based SGI‐1027 as Inhibitors of DNA Methylation

2014 ChemMedChem
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Abstract A87: Synthesis and structure‐activity relationships of a series of epipodophyllotoxin polyamine conjugated derivatives vectorized for active polyamine transporter system in tumor cells, leading to the selection of F14512 for clinical trials

2009 Molecular Cancer Therapeutics
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Establishment and characterization of a human A549 non small cell lung cancer cell line resistant to the novel vectorized cytotoxic drug F14512

2008 Cancer Research
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On the mechanism of action of triptolide, beyond the NF-kB pathway

2006 Cancer Research
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