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Melville C. Osborne

Johnson & Johnson Pharmaceutical Research and Development

8

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Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats.

2005 American Journal of Physiology-endocrinology and Metabolism
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Pharmacological profile of a novel, non‐TZD PPARγ agonist

2005 Diabetes, Obesity and Metabolism
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Reduction in Glucagon Receptor Expression by an Antisense Oligonucleotide Ameliorates Diabetic Syndrome in db/db Mice

2004 Diabetes
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Benzoxazinones as PPARgamma agonists. 2. SAR of the amide substituent and in vivo results in a type 2 diabetes model.

2004 Journal of Medicinal Chemistry
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A Novel Method for Analysis of Nuclear Receptor Function at Natural Promoters: Peroxisome Proliferator-Activated Receptor γ Agonist Actions on aP2 Gene Expression Detected Using Branched DNA Messenger RNA Quantitation

1999 Molecular Endocrinology
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Citations (56)