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Yin Liang

University of Pennsylvania

19

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1551

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Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes

2017 ACS Medicinal Chemistry Letters
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Synthesis and Biological Evaluation of 3-Aryl-3-(4-phenoxy)-propionic Acid as a Novel Series of G Protein-Coupled Receptor 40 Agonists

2007 Journal of Medicinal Chemistry
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Reduction in Glucagon Receptor Expression by an Antisense Oligonucleotide Ameliorates Diabetic Syndrome in db/db Mice

2004 Diabetes
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Systemic treatment with sympatholytic dopamine agonists improves aberrant beta-cell hyperplasia and GLUT2, glucokinase, and insulin immunoreactive levels in ob/ob mice.

2001 Metabolism-clinical and Experimental
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Hyperinsulinemia increases norepinephrine metabolism in the ventromedial hypothalamus of rats.

2000 Neuroreport
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Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (βHC9)

1997 Diabetologia
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Glucose metabolism and insulin release in mouse beta HC9 cells, as model for wild-type pancreatic beta-cells.

1996 American Journal of Physiology-endocrinology and Metabolism
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Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut.

1994 Journal of Biological Chemistry
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Effects of Glucose on Insulin Secretion, Glucokinase Activity, and Transgene Expression in Transgenic Mouse Islets Containing an Upstream Glucokinase Promoter-Human Growth Hormone Fusion Gene

1994 Diabetes
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In situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents.

1994 Journal of Clinical Investigation
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Citations (38)