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Qian Wang

Wilmington University

12

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1373

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Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies

2018 PLOS ONE
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INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

2017 ACS Medicinal Chemistry Letters
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A Novel Kinase Inhibitor, INCB28060, Blocks c-MET–Dependent Signaling, Neoplastic Activities, and Cross-Talk with EGFR and HER-3

2011 Clinical Cancer Research
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Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

2010 Blood
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Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model.

2009 Journal of Medicinal Chemistry
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Selective Inhibition of ADAM Metalloproteases as a Novel Approach for Modulating ErbB Pathways in Cancer

2007 Clinical Cancer Research
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Selective inhibition of ADAM metalloproteases blocks HER-2 extracellular domain (ECD) cleavage and potentiates the anti-tumor effects of trastuzumab

2006 Cancer Biology & Therapy
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Presenilin-1 and 2 are molecular targets for gamma secretase inhibitors

2000 Journal of Biological Chemistry
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