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Douglas A. Melton

Harvard University
Howard Hughes Medical Institute

292

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Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny

2021 Stem Cell Research
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209.2: Engineering Immune-evasive Human Stem Cell-derived Islet Cells

2021 Transplantation
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The promise of stem cell-derived islet replacement therapy.

2021 Diabetologia
- Douglas A. Melton
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A therapeutic convection-enhanced macroencapsulation device for enhancing β cell viability and insulin secretion.

2021 Proceedings of the National Academy of Sciences of the United States of America
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402.4: Genetic Approaches to Attain Hypo-immunogenic Human Stem Cell Derived Islets for Transplantation

2021 Transplantation
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Building Biomimetic Potency Tests for Islet Transplantation.

2021 Diabetes
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A human ESC line for efficient CRISPR editing of pluripotent stem cells.

2021 Stem Cell Research
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209.6: Long-term Functional Survival of Human Stem Cell-derived Islets Microencapsulated in Alginate With CXCL12 in Non-human Primates Without Immunosuppression

2021 Transplantation
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Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis.

2020 Cell Reports
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Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration

2020 eLife
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