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Pieter Fokko van Loo

Erasmus University Rotterdam

12

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368

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A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.

2021 Nature Communications
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820 MCLA-145 is a bispecific IgG1 antibody that inhibits PD-1/PD-L1 signaling while simultaneously activating CD137 signaling on T cells

2020 Journal for ImmunoTherapy of Cancer
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MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis

2019 Expert Opinion on Biological Therapy
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Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice

2012 Blood
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Highly B lymphocyte‐specific tamoxifen inducible transgene expression of CreERT2 by using the LC‐1 locus BAC vector

2009 Genesis
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Transcription Factor Sp3 Knockout Mice Display Serious Cardiac Malformations

2007 Molecular and Cellular Biology
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Surrogate-Light-Chain Silencing Is Not Critical for the Limitation of Pre-B Cell Expansion but Is for the Termination of Constitutive Signaling

2007 Immunity
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Bruton’s Tyrosine Kinase and SLP-65 Regulate Pre-B Cell Differentiation and the Induction of Ig Light Chain Gene Rearrangement

2006 Journal of Immunology
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Impaired hematopoiesis in mice lacking the transcription factor Sp3.

2003 Blood
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Citations (48)