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Louisa Dal Cengio

University of British Columbia

7

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147

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DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease

2020 Frontiers in Cellular Neuroscience
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Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease.

2019 Nucleic Acids Research
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Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease.

2018 Science Translational Medicine
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Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease

2018 BMC Biology
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A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.

2017 Human Molecular Genetics
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Citations (16)