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Shenghua Shi
Shenghua Shi
Pfizer
Chemistry
Glucagon receptor
Biochemistry
Chemical synthesis
Combinatorial chemistry
5
Papers
185
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A simple approach to a multi-objective design with constraints in compound selection for drug discovery
2003
Shenghua Shi
Atsuo Kuki
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Optimization of Alkylidene Hydrazide Based Human Glucagon Receptor Antagonists. Discovery of the Highly Potent and Orally Available 3-Cyano-4-hydroxybenzoic Acid [1-(2,3,5,6-Tetramethylbenzyl)-1H-indol-4-ylmethylene]hydrazide
2002
Journal of Medicinal Chemistry
Peter Madsen
Anthony Lai Ling
Michael Bruno Plewe
Christian Sams
Lotte Bjerre Knudsen
Ulla G. Sidelmann
Lars Ynddal
Christian L. Brand
Birgitte Andersen
Murphy D
Min Teng
Larry Truesdale
Dan Kiel
John May
Atsuo Kuki
Shenghua Shi
Johnson
Kimberly Teston
Jun Feng
James Lakis
Kenna Anderes
Gregor
Jesper Lau
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Citations (82)
Human glucagon receptor antagonists based on alkylidene hydrazides.
2002
Bioorganic & Medicinal Chemistry Letters
Anthony Lai Ling
Michael Bruno Plewe
Javier Gonzalez
Peter Madsen
Christian Sams
Jesper Lau
Vlad E. Gregor
Doug Murphy
Kimberly Teston
Atsuo Kuki
Shenghua Shi
Larry Truesdale
Dan Kiel
John May
James Lakis
Kenna Anderes
Eugenia A. Iatsimirskaia
Ulla G. Sidelmann
Lotte Bjerre Knudsen
Christian L. Brand
Alex Polinsky
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Citations (39)
Identification of alkylidene hydrazides as glucagon receptor antagonists.
2001
Journal of Medicinal Chemistry
Anthony Lai Ling
Yufeng Hong
Javier Gonzalez
Vlad E. Gregor
Alex Polinsky
Atsuo Kuki
Shenghua Shi
Kimberly Teston
Douglas Murphy
John B. Porter
Dan Kiel
James Lakis
Kenna Anderes
John May
Lotte Bjerre Knudsen
Jesper Lau
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Citations (43)
Efficient combinatorial filtering for desired molecular properties of reaction products.
2000
Journal of Molecular Graphics & Modelling
Shenghua Shi
Zhengwei Peng
Jaroslaw Kostrowicki
Genevieve Paderes
Atsuo Kuki
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Citations (21)
1