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Allan Olson

Celgene

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DOP05 Target engagement and pharmacodynamic biomarker analysis following treatment with the oral gut-targeted HIF-1α stabilizer GB004 in a Phase 1b trial in Active Ulcerative Colitis

2021 Journal of Crohn's and Colitis
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P540 GB004, a novel prolyl hydroxylase inhibitor for inflammatory bowel disease, leads to gut-targeted HIF-1α pathway engagement in a multiple-dose study in healthy subjects

2020 Journal of Crohns & Colitis
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Ozanimod induction therapy for patients with moderate to severe Crohn's disease: a single-arm, phase 2, prospective observer-blinded endpoint study

2020 The Lancet Gastroenterology & Hepatology
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Long-Term Efficacy and Safety of RPC4046, an Anti-Interleukin-13 Monoclonal Antibody, in Patients With Eosinophilic Esophagitis: Results From the Open-Label Extension of the HEROES Study

2019 The Journal of Allergy and Clinical Immunology
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A composite disease activity index for early drug development in ulcerative colitis: development and validation of the UC-100 score

2019 The Lancet Gastroenterology & Hepatology
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Efficacy of RPC4046, an Anti-Interleukin-13 Monoclonal Antibody, in Patients With Active Eosinophilic Esophagitis: Analysis of the Steroid-Refractory Subgroup From the HEROES Study

2019 The Journal of Allergy and Clinical Immunology
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Markers of Esophageal Epithelial-Mesenchymal Transition Are Significantly Reduced in Active Eosinophilic Esophagitis Following 16 Weeks of Treatment With RPC4046, an Anti-Interleukin-13 Monoclonal Antibody

2019 The Journal of Allergy and Clinical Immunology
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RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis

2019 Gastroenterology
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Sa1111 - Markers of Esophageal Epithelial-Mesenchymal Transition (Emt) are Significantly Reduced in Active Eosinophilic Esophagitis Following 16 Weeks of Treatment with Rpc4046, an Anti-Interleukin-13 Monoclonal Antibody

2018 Gastroenterology
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Cardiac Safety of Ozanimod, a Novel Sphingosine‐1‐Phosphate Receptor Modulator: Results of a Thorough QT/QTc Study

2018 Clinical pharmacology in drug development
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