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Barrett G. Levesque

University of California, San Diego
University of Western Ontario

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DOP05 Target engagement and pharmacodynamic biomarker analysis following treatment with the oral gut-targeted HIF-1α stabilizer GB004 in a Phase 1b trial in Active Ulcerative Colitis

2021 Journal of Crohn's and Colitis
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Fr150 GB004 EXHIBITS PROTECTIVE EFFECTS DIRECTLY ON EPITHELIAL CELLS USING EX VIVO ORGANOID AND MONOLAYER CULTURES

2021 Gastroenterology
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P540 GB004, a novel prolyl hydroxylase inhibitor for inflammatory bowel disease, leads to gut-targeted HIF-1α pathway engagement in a multiple-dose study in healthy subjects

2020 Journal of Crohns & Colitis
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Reliability of Measuring Ileo-Colonic Disease Activity in Crohn's Disease by Magnetic Resonance Enterography

2018 Inflammatory Bowel Diseases
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Disease activity indices in coeliac disease: systematic review and recommendations for clinical trials

2018 Gut
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Development of reliable, valid and responsive scoring systems for endoscopy and histology in animal models for inflammatory bowel disease

2018 Journal of Crohns & Colitis
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Performance of Crohn’s disease Clinical Trial Endpoints based upon Different Cutoffs for Patient Reported Outcomes or Endoscopic Activity: Analysis of EXTEND Data

2018 Inflammatory Bowel Diseases
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Corrigendum: Evolving Concepts in Phases I and II Drug Development for Crohn’s Disease

2018 Journal of Crohns & Colitis
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Corrigendum: Responsiveness of Endoscopic Indices of Disease Activity for Crohn’s Disease

2017 The American Journal of Gastroenterology
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Optimizing the quality of endoscopy in inflammatory bowel disease: focus on surveillance and management of colorectal dysplasia using interactive image- and video-based teaching

2017 Gastrointestinal Endoscopy
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