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David A. Egan

Netherlands Cancer Institute

17

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3250

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Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia

2019 Pediatric Blood & Cancer
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Abstract 2630: Preclinical identification of Venetoclax combination strategies with Idasanutlin, CUDC-907, Prexasertib or Talazoparib for neuroblastoma treatment

2018 Cancer Research
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A Genome-wide Multidimensional RNAi Screen Reveals Pathways Controlling MHC Class II Antigen Presentation

2011 Cell
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Discovery and Optimization of Boronic Acid Based Inhibitors of Autotaxin

2010 Journal of Medicinal Chemistry
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Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation

2010 Proceedings of the National Academy of Sciences of the United States of America
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High-throughput T-cell epitope discovery through MHC peptide exchange.

2009 Methods of Molecular Biology
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Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1

2007 Nature
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Regulation of the p27Kip1 tumor suppressor by miR‐221 and miR‐222 promotes cancer cell proliferation

2007 The EMBO Journal
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C-terminal modifications of nonpeptide renin inhibitors: improved oral bioavailability via modification of physicochemical properties.

1992 Journal of Medicinal Chemistry
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Nonpeptide renin inhibitors employing a novel 3-aza (or oxa)-2,4-dialkyl glutaric acid moiety as a P2/P3 amide bond replacement

1992 Journal of Medicinal Chemistry
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Citations (15)