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Susie A. Lee

University of California, San Francisco

8

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761

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AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathways.

2012 Hepatology
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Inactivation of Spry2 accelerates AKT-driven hepatocarcinogenesis via activation of MAPK and PKM2 pathways

2012 Journal of Hepatology
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RNA interference as therapeutics for hepatocellular carcinoma.

2011 Recent Patents on Anti-cancer Drug Discovery
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Synergistic role of Sprouty2 inactivation and c-Met up-regulation in mouse and human hepatocarcinogenesis.

2010 Hepatology
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Role of cyclin D1 as a mediator of c-Met- and beta-catenin-induced hepatocarcinogenesis.

2009 Cancer Research
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Citations (56)