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Timothy Mant

Guy's Hospital
Quintiles

47

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2112

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Impact of voxelotor (GBT440) on unconjugated bilirubin and jaundice in sickle cell disease

2018 Hematology Reviews
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Impact of GBT440 on Unconjugated Bilirubin and Jaundice in Sickle Cell Disease: A Patient Case Report

2017 Blood
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Safety and patient response as indicated by biomarker changes to binding immunoglobulin protein in the phase I/IIA RAGULA clinical trial in rheumatoid arthritis

2016 Rheumatology
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Long-Term Dosing in Sickle Cell Disease Subjects with GBT440, a Novel HbS Polymerization Inhibitor

2016 Blood
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The effect of prasugrel on ADP-stimulated markers of platelet activation in patients with sickle cell disease

2015 Platelets
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Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial

2014 The Lancet
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A phase 1 study of prasugrel in patients with sickle cell disease

2013 British Journal of Clinical Pharmacology
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A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects onex vivoplatelet reactivity: Prasugrel in patients with sickle cell disease

2013 British Journal of Clinical Pharmacology
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Abstract 67: Phase I Safety, Pharmacokinetic, and Pharmacodynamic Results for ALN-PCS, a Novel RNAi Therapeutic for the Treatment of Hypercholesterolemia

2012 Arteriosclerosis, Thrombosis, and Vascular Biology
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A textbook of clinical pharmacology

2012
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