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Jeng Yie Chan

Garvan Institute of Medical Research

20

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Phlda3 regulates beta cell survival during stress

2019 Scientific Reports
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Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans

2019 Diabetologia
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Deletion distal to the PAX6 coding region reveals a novel basis for familial cosegregation of aniridia and diabetes mellitus

2019 Diabetes Research and Clinical Practice
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Evidence against a role for NLRP3-driven islet inflammation in db/db mice

2018 Molecular metabolism
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On-target action of anti-tropomyosin drugs regulates glucose metabolism

2018 Scientific Reports
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Inhibition of Y1 receptor signaling improves islet transplant outcome.

2017 Nature Communications
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A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.

2016 PLOS Genetics
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Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells

2016 Diabetologia
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Inhibitor of differentiation proteins protect against oxidative stress by regulating the antioxidant–mitochondrial response in mouse beta cells

2015 Diabetologia
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Hypoxia induces beta cell death by inhibiting the adaptive UPR.

2015
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