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Michael N. Dudley

University of Rhode Island
Roger Williams Medical Center

184

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5600

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A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Biapenem in Healthy Adult Subjects.

2021 Antimicrobial Agents and Chemotherapy
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In Vitro Activity of the Ultra-Broad-Spectrum Beta-lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa.

2021 Antimicrobial Agents and Chemotherapy
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Population Pharmacokinetics of Meropenem and Vaborbactam Based on Data from Non-Infected Subjects and Infected Patients

2021 Antimicrobial Agents and Chemotherapy
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QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics.

2021 Frontiers in Microbiology
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Selection of QPX7831, an Orally Bioavailable Prodrug of Boronic Acid β-Lactamase Inhibitor QPX7728.

2021 Journal of Medicinal Chemistry
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The Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultra-Broad-Spectrum Beta-lactamase Inhibitor of Serine and Metallo Beta-Lactamases in Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii.

2020 Antimicrobial Agents and Chemotherapy
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Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultra-Broad-Spectrum Beta-lactamase Inhibitor of Serine and Metallo Beta-Lactamases: Enhancement of Activity of Multiple Antibiotics Against Isogenic Strains Expressing Single β-lactamases.

2020 Antimicrobial Agents and Chemotherapy
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In Vitro Activity of the Ultra-Broad-Spectrum Beta-lactamase Inhibitor QPX7728 against Carbapenem-Resistant Enterobacterales (CRE) With Varying Intrinsic and Acquired Resistance Mechanisms.

2020 Antimicrobial Agents and Chemotherapy
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In Vitro Activity of the Ultra-Broad-Spectrum Beta-lactamase Inhibitor QPX7728 in Combination with Meropenem against Clinical Isolates of Carbapenem-Resistant Acinetobacter baumannii.

2020 Antimicrobial Agents and Chemotherapy
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Discovery of Cyclic Boronic Acid QPX7728, an Ultra-broad-spectrum Inhibitor of Serine and Metallo Beta-lactamases.

2020 Journal of Medicinal Chemistry
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Citations (55)