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Orville A. Pemberton

University of South Florida

6

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Mechanism of proton transfer in class A β-lactamase catalysis and inhibition by avibactam

2020 Proceedings of the National Academy of Sciences of the United States of America
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Structural basis for substrate specificity and carbapenemase activity of OXA-48 Class D β-lactamase

2020 ACS Infectious Diseases
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Structural basis and binding kinetics of vaborbactam in class A β-lactamase inhibition

2020 Antimicrobial Agents and Chemotherapy
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KPC-2 β-lactamase Enables Carbapenem Antibiotic Resistance Through Fast Deacylation of the Covalent Intermediate.

2020 Journal of Biological Chemistry
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Heteroaryl phosphonates as non-covalent inhibitors of both serine and metallo-carbapenemases.

2019 Journal of Medicinal Chemistry
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