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Carol Terminelli

Schering-Plough

19

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607

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Synthesis and structure-activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists.

2008 Bioorganic & Medicinal Chemistry Letters
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Discovery of 2-Hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist

2006 Journal of Medicinal Chemistry
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The anti-inflammatory activities of cannabinoid receptor ligands in mouse peritonitis models

2001 European Journal of Pharmacology
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Modulation of cytokine responses in Corynebacterium parvum-primed endotoxemic mice by centrally administered cannabinoid ligands.

2001 European Journal of Pharmacology
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Effects of Cannabinoid Receptor Agonist and Antagonist Ligands on Production of Inflammatory Cytokines and Anti-Inflammatory Interleukin-10 in Endotoxemic Mice

2000 Journal of Pharmacology and Experimental Therapeutics
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Endogenous mouse interleukin-10 is up-regulated by exogenously administered recombinant human interleukin-10, but does not contribute to the efficacy of the human protein in mouse models of endotoxemia.

1999 Immunopharmacology
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Elevated levels of NO in both unchallenged and LPS-challenged C. parvum-primed mice are attributable to the activity of a cytokine-inducible isoform of iNOS.

1997 Journal of Leukocyte Biology
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Inhibitory effects of recombinant human interleukin 10 on disease manifestations in a P-->F1 model of acute graft versus host disease.

1995 Transplantation
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Synthesis of dibenzo[a,d]cycloheptanes as cytokine biosynthesis inhibitors

1995 Bioorganic & Medicinal Chemistry Letters
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The cooperative effects of TNF-α and IFN-γ are determining factors in the ability of IL-10 to protect mice from lethal endotoxemia

1994 Journal of Leukocyte Biology
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Citations (41)