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John Sensintaffar
John Sensintaffar
Biogen Idec
Hsp90
Molecular biology
Hsp90 inhibitor
Heat shock protein
Chaperone (protein)
4
Papers
1196
Citations
0.01
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Assessing efficacy of novel Hsp90 inhibitors in breast cancer patients by enumeration of circulating tumor cells and HER-2 degradation
2008
Cancer Research
Naveen Dakappagari
John Sensintaffar
William McAuliffe
Lori Hipolito
Adeela Kamal
Karen Lundgren
Francis Burrows
Shabnam Tangri
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Proteomics analysis of Hsp90 modulation
2007
Molecular Cancer Therapeutics
Jing Wei
Mark Daniels
Ben Colson
Diem Tran
John Sensintaffar
Noel Timple
Naveen Dakappagari
Adeela Kamal
Karen Lundgren
Ingrid Joseph
Shabnam Tangri
Chris Storgard
Alessandra Cesano
Steve French
Francis Burrows
Alex Buko
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BIIB021 is a small molecule inhibitor of the heat shock protein, Hsp90, that shows potent anti-tumor activity in preclinical models
2007
Molecular Cancer Therapeutics
Karen Lundgren
Hong Zhang
Adeela Kamal
Rachel Lough
Noelito Timple
John Sensintaffar
David J. Busch
Cindy Yang
Laura Neely
Samina Khan
Kevin Hong
Srinivas Rao Kasibhatla
Marcus F. Boehm
Francis Burrows
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A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors.
2003
Nature
Adeela Kamal
Lia Thao
John Sensintaffar
Lin Zhang
Marcus F. Boehm
Lawrence C. Fritz
Francis Burrows
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Citations (1193)
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