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Ingrid Joseph

Biogen Idec

12

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356

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Development of an Fn14 agonistic antibody as an anti-tumor agent

2011 mAbs
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Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.

2011 Bioorganic & Medicinal Chemistry Letters
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Stable IgG-like Bispecific Antibodies Directed toward the Type I Insulin-like Growth Factor Receptor Demonstrate Enhanced Ligand Blockade and Anti-tumor Activity

2011 Journal of Biological Chemistry
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A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity

2011 mAbs
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CS4-2 Efficacy of pegylated interferon β-1a in human cancer xenograft models

2010 Cytokine
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Combination of Two Insulin-Like Growth Factor-I Receptor Inhibitory Antibodies Targeting Distinct Epitopes Leads to an Enhanced Antitumor Response

2010 Molecular Cancer Therapeutics
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105 BIIB024, a potent pan-Raf kinase inhibitor for melanoma and solid tumors

2010 Ejc Supplements
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BIIB022, a human antibody targeting human insulin-like growth factor-1 receptor (IGF-1R), enhances the anti-tumor activities of Tarceva in non-small cell lung carcinoma (NSCLC) and Rapamycin in sarcoma cell lines

2008 Cancer Research
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Proteomics analysis of Hsp90 modulation

2007 Molecular Cancer Therapeutics
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